Drug Target Optimization in Chronic Myeloid Leukemia Using Innovative Computational Platform
نویسندگان
چکیده
منابع مشابه
Drug Target Optimization in Chronic Myeloid Leukemia Using Innovative Computational Platform
Chronic Myeloid Leukemia (CML) represents a paradigm for the wider cancer field. Despite the fact that tyrosine kinase inhibitors have established targeted molecular therapy in CML, patients often face the risk of developing drug resistance, caused by mutations and/or activation of alternative cellular pathways. To optimize drug development, one needs to systematically test all possible combina...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep08190